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  2. PI-RADS - Wikipedia

    en.wikipedia.org/wiki/PI-RADS

    In a 2015 articles in the Journal of Urology, Thompson reported multi-parametric MRI detection of significant prostate cancer had sensitivity of 96%, specificity of 36%, negative predictive value and positive predictive values of 92% and 52%; when PI-RADS was incorporated into a multivariate analysis (PSA, digital rectal exam, prostate volume ...

  3. Prostate cancer - Wikipedia

    en.wikipedia.org/wiki/Prostate_cancer

    Prostate cancer is a major topic of ongoing research. From 2016 to 2020, over $1.26 billion was invested in prostate cancer research, representing around 5% of global cancer research funds. [122] This places prostate cancer 10th among 18 common cancer types in funding per cancer death, and 9th in funding per disability-adjusted life year lost ...

  4. Prostate cancer screening - Wikipedia

    en.wikipedia.org/wiki/Prostate_cancer_screening

    Prostate cancer antigen 3 is a urine test that detects the overexpression of the PCA3 gene, an indicator of prostate cancer. [32] [46] [47] [44] ConfirmMDx is performed on tissue taken during a prostate biopsy. The test identifies men with clinically significant prostate cancer who would benefit from further testing and treatment.

  5. Management of prostate cancer - Wikipedia

    en.wikipedia.org/wiki/Management_of_prostate_cancer

    A small prospective study published in European Urology in February 2015 assessed the focal treatment of index lesions with HIFU in patients with multifocal prostate cancer and found that the majority of men returned to baseline genitourinary function and 86% of men were free of clinically significant prostate cancer at one year. [35]

  6. High-grade prostatic intraepithelial neoplasia - Wikipedia

    en.wikipedia.org/wiki/High-grade_prostatic...

    There are several reasons why PIN is the most likely prostate cancer precursor. [3] PIN is more common in men with prostate cancer. High grade PIN can be found in 85 to 100% of radical prostatectomy specimens, [4] nearby or even in connection with prostate cancer. It tends to occur in the peripheral zone of the prostate.

  7. Prostate cancer staging - Wikipedia

    en.wikipedia.org/wiki/Prostate_cancer_staging

    Prostate cancer staging is the process by which physicians categorize the risk of cancer having spread beyond the prostate, or equivalently, the probability of being cured with local therapies such as surgery or radiation. Once patients are placed in prognostic categories, this information can contribute to the selection of an optimal approach ...

  8. Amgen (AMGN) Q4 2024 Earnings Call Transcript - AOL

    www.aol.com/finance/amgen-amgn-q4-2024-earnings...

    Our first-in-class STEAP1 CD3 bispecific T cell engager, Xaluritamig, has entered Phase 3 clinical development with a study in post-taxane metastatic castration-resistant prostate cancer.

  9. Active surveillance of prostate cancer - Wikipedia

    en.wikipedia.org/wiki/Active_surveillance_of...

    In a separate study of men from the pre prostate cancer screening era managed with watchful waiting (56% over age 70 years), progression to distant metastasis or prostate cancer death was 13.9% and 12.3%, respectively for Gleason score 6 or below, but considerably higher at 18.2 and 22.7%, 30% and 20%, 44.4% and 55.6% for Gleason 3+4, 4+3, and ...