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In countries where B 12 deficiency is common, it is generally assumed that there is a greater risk of developing anemia. However, the overall contribution of vitamin B 12 deficiency to the global incidence of anemia may not be significant, except in elderly individuals, vegetarians, cases of malabsorption and some genetic disorders. [85]
There is no advantage to the use of adenosylcobalamin or methylcobalamin forms for the treatment of vitamin B 12 deficiency. [20] [21] [4] Hydroxocobalamin can be injected intramuscularly to treat vitamin B 12 deficiency. It can also be injected intravenously for the purpose of treating cyanide poisoning, as the hydroxyl group is displaced by ...
The Schilling test distinguished PA from other forms of B 12 deficiency, [50] specifically, from Imerslund–Gräsbeck syndrome, a B 12-deficiency caused by mutations in CUBN that codes for cubilin the cobalamin receptor. [1] Vitamin B12 deficiency is also prevalent in patients having Crohn's disease (CD) so it should be differentiated. [62]
Other symptoms of vitamin B12 deficiency include memory loss, fatigue and weakness, nerve damage causing numbness and tingling in the arms and legs, dementia, depression, and seizures.
Symptoms “A B12 deficiency can cause physical and neurological symptoms, and research is also growing to support that it can also cause psychological issues as well,” says Shapiro.
Couple that with the fact that older adults are more likely to have trouble fully absorbing vitamin B12, putting them at risk for a deficiency, and doctors say that vitamin B12 deficiency should ...