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A fasciculation, or muscle twitch, is a spontaneous, involuntary muscle contraction and relaxation, involving fine muscle fibers. [1] They are common, with as many as 70% of people experiencing them. [1] They can be benign, or associated with more serious conditions. [1]
The strength of skeletal muscle contractions can be broadly separated into twitch, summation, and tetanus. A twitch is a single contraction and relaxation cycle produced by an action potential within the muscle fiber itself. [27]
This occurs when a muscle's motor unit is stimulated by multiple impulses at a sufficiently high frequency. Each stimulus causes a twitch. If stimuli are delivered slowly enough, the tension in the muscle will relax between successive twitches. If stimuli are delivered at high frequency, the twitches will overlap, resulting in tetanic contraction.
Temporal motor unit recruitment, or rate coding, deals with the frequency of activation of muscle fiber contractions. Consecutive stimulation on the motor unit fibers from the alpha motor neuron causes the muscle to twitch more frequently until the twitches "fuse" temporally. This produces a greater force than singular contractions by ...
Learn how fast-twitch vs slow-twitch muscle fibers influence your performance. Plus, what to know about the role your genetics and training play.
Muscle tissue treated with a non-depolarizing neuromuscular blocking agents will produce an indicative response in the form of a tetanic fade, a diminishing response to tetanic stimulation where the initial intensity will be the highest, and the following ones will show lower and lower strength of response. [1] [2]
Benign fasciculation syndrome (BFS) is characterized by fasciculation (twitching) of voluntary muscles in the body. [1] The twitching can occur in any voluntary muscle group but is most common in the eyelids, arms, hands, fingers, legs, and feet. The tongue can also be affected. The twitching may be occasional to continuous. [2]
NMT is a diverse disorder. As a result of muscular hyperactivity, patients may present with muscle cramps, stiffness, myotonia-like symptoms (slow relaxation), associated walking difficulties, hyperhidrosis (excessive sweating), myokymia (quivering of a muscle), fasciculations (muscle twitching), fatigue, exercise intolerance, myoclonic jerks and other related symptoms.