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This is a list of antiandrogens, [1] or drugs that prevent the effects of androgens like testosterone and dihydrotestosterone (DHT). [2] It includes direct antagonists of the androgen receptor (AR), androgen synthesis inhibitors like 5α-reductase inhibitors and CYP17A1 inhibitors , and antigonadotropins like GnRH analogues , estrogens , and ...
3β-Hydroxysteroid dehydrogenase inhibitors (3β-HSD inhibitors): inhibit the conversion of weaker androgens such as dehydroepiandrosterone (DHEA) and androstenediol into more potent androgens like and testosterone; Cholesterol side-chain cleavage enzyme inhibitors (P450SCC/CYP11A1 inhibitors): inhibit the synthesis of pregnenolone from ...
Androgen synthesis inhibitors: Drugs that directly inhibit the enzymatic biosynthesis of androgens like testosterone and/or DHT. [ 89 ] [ 31 ] Examples include the CYP17A1 inhibitors ketoconazole , abiraterone acetate , and seviteronel , [ 89 ] the CYP11A1 (P450scc) inhibitor aminoglutethimide , [ 89 ] and the 5α-reductase inhibitors ...
Besides foods that lower testosterone levels, a few other things may influence hormonal imbalances or lead to low testosterone. This includes: Side effects from medication
Steroidogenesis inhibitors are analogous in effect and use to antigonadotropins (which specifically inhibit gonadal sex steroid production), but work via a different mechanism of action; whereas antigonadotropins suppress gonadal production of sex steroids by effecting negative feedback on and thereby suppressing the hypothalamic–pituitary ...
Even as we age, our testosterone production begins to decrease. Luckily, though, there's several ways to help achieve proper levels. Yes, your doctor can prescribe testosterone supplements to help ...
This is a list of 5α-reductase inhibitors (5α-RIs), drugs which inhibit one or more isoforms of the enzyme 5α-reductase.This enzyme is responsible for the conversion of the androgen hormone testosterone into the more potent dihydrotestosterone (DHT) and is essential for the production of neurosteroids like allopregnanolone, tetrahydrodeoxycorticosterone (THDOC), and 3α-androstanediol from ...
Studies have demonstrated that some of these products inhibit 17β-hydroxysteroid dehydrogenase and 17,20-lyase, which catalyzes the conversion of 17α-hydroxyprogesterone to androstenedione to testosterone. [9] In one study a group of men were given an anaphrodisiac and the effect on the metabolism of mineralocorticoids in these men was recorded.