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There was a prevailing view that Crohn's disease is a primary T cell autoimmune disorder; however, a newer theory hypothesizes that Crohn's results from an impaired innate immunity. [121] The later hypothesis describes impaired cytokine secretion by macrophages , which contributes to impaired innate immunity and leads to a sustained microbial ...
The Crohn's & Colitis Foundation (The Foundation) is a volunteer fueled non-profit organization in the US that works to fund research to find cures for Crohn's disease and ulcerative colitis, collectively known as inflammatory bowel disease (IBD), and to improve the quality of life of children and adults affected by these digestive diseases.
The Crohn's Disease Activity Index or CDAI is a research tool used to quantify the symptoms of patients with Crohn's disease.This is of useful importance in research studies done on medications used to treat Crohn's disease; most major studies on newer medications use the CDAI in order to define response or remission of disease.
Infobox for medical conditions Template parameters [Edit template data] This template prefers block formatting of parameters. Parameter Description Type Status name name Name of disease or medical condition (should be the same as the title of the article) Example Posttraumatic stress disorder String required synonym synonym synonyms Common terms for the illness or condition. Example Upper ...
To change this template's initial visibility, the |state= parameter may be used: {{Inflammatory bowel disease | state = collapsed}} will show the template collapsed, i.e. hidden apart from its title bar. {{Inflammatory bowel disease | state = expanded}} will show the template expanded, i.e. fully visible.
Crohn preferred using the medically descriptive terms "regional ileitis" and "regional enteritis" to "Crohn's disease". Some of Crohn's initial research into the causes of the Crohn's disease was centered around his personal conviction [citation needed] that it was caused by the same pathogen, a bacterium called Mycobacterium paratuberculosis ...
It was founded in 1979 as the National Association for Colitis and Crohn's Disease. Crohn's & Colitis UK brings together people of all ages who have Crohn's or colitis, their families, and the health professionals involved in their care. These two illnesses are both forms of Iinflammatory bowel disease (IBD) and they affect over 500,000 people ...
In Crohn's disease, surgery involves removing the worst inflamed segments of the intestine and connecting the healthy regions, but unfortunately, it does not cure Crohn's or eliminate the disease. At some point after the first surgery, Crohn's disease can recur in the healthy parts of the intestine, usually at the resection site. [76] (For ...