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  2. Apixaban - Wikipedia

    en.wikipedia.org/wiki/Apixaban

    Apixaban is recommended by the National Institute for Health and Clinical Excellence for the prevention of stroke and systemic embolism in people with non-valvular atrial fibrillation and at least one of the following risk factors: prior stroke or transient ischemic attack, age 75 years or older, diabetes, or symptomatic heart failure.

  3. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    The p-methoxy group of apixaban connects to S1 pocket of FXa but does not appear to have any interaction with any residues in this region of FXa. The pyrazole N-2 nitrogen atom of apixaban interacts with Gln-192 and the carbonyl oxygen interacts with Gly-216. The phenyl lactam group of apixaban is positioned between Tyr-99 and Phe-174 and due ...

  4. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    Side effects may include bleeding, most commonly from the nose, gastrointestinal tract (GI) or genitourinary system. [2] Compared to the risk of bleeding with warfarin use, direct factor Xa inhibitors have a higher risk of GI bleeding, but lower risk of bleeding in the brain. [2]

  5. 17 New Anti-Inflammatory Dinners to Make This Week - AOL

    www.aol.com/17-anti-inflammatory-dinners-week...

    Heami Lee, Food Stylist: Emily Nabors Hall, Prop Stylist: Christine Keeley Tuna provides protein and omega-3 fatty acids, while the addition of Greek-style yogurt in the dressing helps amp up the ...

  6. In just three minutes, your wine will be purified and leave ...

    www.aol.com/lifestyle/just-three-minutes-wine...

    It purifies and aerates your glass of wine in as little as three minutes, helping prevent common side effects of drinking the histamines and sulfites in wine, like headaches, upset stomach ...

  7. Betrixaban - Wikipedia

    en.wikipedia.org/wiki/Betrixaban

    Previously apixaban and rivaroxaban have failed to show positive risk/benefit ratio in this indication compared to enoxaparin. [9] [10] [non-primary source needed] APEX trial compared betrixaban with enoxaparin and included 7513 patients. Lower rate of VTE events was found in betrixaban arm with no increase in major bleedings compared to ...

  8. Taco Bell security guard brutally slaps female customer, wild ...

    www.aol.com/news/taco-bell-security-guard...

    She got served a crunch-slap supreme. A security guard at a California Taco Bell was caught on video viciously slapping a rambunctious customer who refused to leave the chain restaurant on Sunday.

  9. Anticoagulant - Wikipedia

    en.wikipedia.org/wiki/Anticoagulant

    An anticoagulant, commonly known as a blood thinner, is a chemical substance that prevents or reduces the coagulation of blood, prolonging the clotting time. [1] Some occur naturally in blood-eating animals, such as leeches and mosquitoes, which help keep the bite area unclotted long enough for the animal to obtain blood.