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Hypothyroidism is classified as either primary, secondary, or tertiary. Primary hypothyroidism is for when the cause is due to an abnormality of the thyroid gland, secondary hypothyroidism is when the cause is decreased thyroid-stimulating hormone levels, and tertiary hypothyroidism is when the cause is an inadequate amount of thyrotropin-releasing hormone being released.
If Cushing's is suspected it can be confirmed via urinalysis of the creatine/cortisol ratio. L-thyroxine is the most common method of treating hypothyroidism in dogs, if used to treat a dog with Cushing's the dog will likely display polyuria and polydipsia and the condition may worsen. [13]
Prescribing thyroxine to treat this may lead to lifelong thyroid overtreatment. [2] Hyperthyroidism may be assumed due to decreased TSH and a transient fT4 increase. In some cases, this can be distinguished from NTIS by a thyroid ultrasound, which is commonly available in the hospital intensive care unit. [2]
Hypothyroidism is the most common endocrine disease in dogs. It can be caused by autoimmune destruction (lymphocytic thyroiditis) or idiopathic atrophy of the thyroid gland. [101] These two causes are responsible for over 95% of the hypothyroidism cases in dogs. [102]
Certain medications can have the unintended side effect of affecting thyroid function. While some medications can lead to significant hypothyroidism or hyperthyroidism and those at risk will need to be carefully monitored, some medications may affect thyroid hormone lab tests without causing any symptoms or clinical changes, and may not require treatment.
One of them, Billy, has become one of the first dozen pets to be injected with a gene therapy treatment intended to extend dog longevity. "I was thrilled to get him into the program," Crommett said.