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A commercially prepared pre-filled syringe of metaraminol for bolus use during anaesthesia, made up as 0.5 mg/mL (2.5 mg in 5 mL). Metaraminol is given intravenously as either a bolus (often 0.5–1 mg doses) or as an infusion, usually via peripheral intravenous access. Metaraminol is commonly available as 10 mg in 1 mL, that requires dilution ...
[4] [5] Dosages of oral estriol of 4 to 10 mg have been found to result in a fairly large range of maximal estriol levels of 80 to 340 pg/mL. [5] After a single oral dose of 8 mg estriol in postmenopausal women, maximal levels of 65 pg/mL estriol and 60 ng/mL estriol conjugates were produced within an hour. [ 4 ]
Estradiol valerate is and has been available in the form of vials and ampoules of oil solution for intramuscular injection in concentrations of 4, 5, 10, 20, and 40 mg/mL and in the form of oral tablets at doses of 0.5, 1, 2, and 4 mg per tablet.
Oral syringes are available in various sizes, from 1–10 mL and larger. An oral syringe is typically purple in colour to distinguish it from a standard injection syringe with a luer tip. [ 24 ] The sizes most commonly used are 1 mL, 2.5 mL, 3 mL, 5 mL and 10 mL.
Equipment include syringes calibrated in tenths and hundredths of a milliliter. The dosage given is usually less than 0.5 mL, less than given subcutaneously or intramuscularly. A 1 ⁄ 4-to-1 ⁄ 2-inch-long (6 to 13 mm) and 26 or 27 gauge thick hypodermic needle is used. [1]
HELIOS-A (NCT03759379) was a phase III, global, open-label study comparing the efficacy and safety of vutrisiran to patisiran. 164 ATTRv amyloidosis patients were randomized 3:1 to subcutaneous vutrisiran 25 mg every 3 months or patisiran 0.3 mg/kg IV infusion every 3 weeks for 18 months’ treatment period to be followed by a lengthier ...
[Glucose](mg/dl) D5W: 5% Dextrose 0 0 278 5000 2/3 D5W & 1/3 NS 3.3% Dextrose / 0.3% saline 51 51 185 3333 Half-normal saline: 0.45% NaCl 77 77 0 0 Normal saline: 0.9% NaCl 154 154 0 0 Ringer's lactate: Lactated Ringer 130 109 0 0 D5NS: 5% Dextrose, Normal Saline 154 154 278 5000
It is available in a sealed pack that contains freeze-dried human fibrinogen (20 mg/0.5 ml), freeze-dried human thrombin (250 IU/0.5 ml), aprotinin solution (1,500 KIU in 0.5 ml), one ampoule of sterile water, four 21-gauge needles, two 20-gauge blunt application needles, an applicator with two mixing chambers, and one plunger guide.