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Albendazole is a broad-spectrum antihelmintic and antiprotozoal agent of the benzimidazole type. [3] It is used for the treatment of a variety of intestinal parasite infections, including ascariasis, pinworm infection, hookworm infection, trichuriasis, strongyloidiasis, taeniasis, clonorchiasis, opisthorchiasis, cutaneous larva migrans, giardiasis, and gnathostomiasis, among other diseases.
Deworming programmes for children usually administer an anthelmintic drug such as albendazole or mebendazole (or praziquantel in a weight based or height based dose for schistosomiasis). The treatment is given as a single dose in a pill formulation. [3] [5] Other drugs used, though not approved by the WHO, include pyrantel pamoate, piperazine ...
Hookworm is closely associated with poverty because it is most often found in impoverished areas, and its symptoms promote poverty through the educational and health effects it has on children. [2] It is the leading cause of anemia and undernutrition in developing countries, while being one of the most commonly occurring diseases among poor ...
In the first mass deworming programme involving CWW, one million Ethiopean children were given mebendazole in 2007, and since 2013 annual mass deworming reached six million. [21] 14 endemic countries were covered during the first phase up to 2012. [22]
Anthelmintic medication is also used in mass deworming campaigns of school-aged children in many developing countries. [2] [3] Anthelmintics are also used for mass deworming of livestock. The drugs of choice for soil-transmitted helminths are mebendazole and albendazole; [4] for schistosomiasis and tapeworms it is praziquantel. [5]
A lower dose should be used in people with liver disease. [2] While it does not appear to be harmful during pregnancy, it has not been studied for this use. [3] It is unclear if it is safe for use during breastfeeding. [2] It is in the antihelmintic family of medications. [4] It works by paralyzing worms. [4] Pyrantel was initially described in ...
In humans, mebendazole (200–400 mg three times a day for three days) or albendazole (400 mg twice a day for 8–14 days) is given to treat trichinosis. [36] These drugs prevent newly hatched larvae from developing, but should not be given to pregnant women or children under two years of age.
A 2008 review found that the efficacy of single-dose treatments for hookworm infections were as follows: 72% for albendazole, 15% for mebendazole, and 31% for pyrantel pamoate. [29] This substantiates prior claims that albendazole is much more effective than mebendazole for hookworm infections.