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  2. Tandem affinity purification - Wikipedia

    en.wikipedia.org/wiki/Tandem_Affinity_Purification

    A research by EMBO (Dziembowski, 2004) identified a new complex required for nuclear pre-mRNA retention and splicing. They have purified a novel trimeric complex composed of 3 other subunits (Snu17p, Bud13p and Pml1p) and find that these subunits are not essential for viability but required for efficient splicing (removal of introns) of pre-mRNA.

  3. Transcriptomics technologies - Wikipedia

    en.wikipedia.org/wiki/Transcriptomics_technologies

    Since gene regulation may occur at the mRNA isoform level, splice-aware alignments also permit detection of isoform abundance changes that would otherwise be lost in a bulked analysis. [ 114 ] De novo assembly can be used to align reads to one another to construct full-length transcript sequences without use of a reference genome. [ 115 ]

  4. Bell System Practices - Wikipedia

    en.wikipedia.org/wiki/Bell_System_Practices

    A typical volume of Bell System Practices from the 1970s. The Bell System Practices (BSPs) is a compilation of technical publications which describes the best methods of engineering, constructing, installing, and maintaining the telephone plant of the Bell System under direction of AT&T and Bell Telephone Laboratories. [1]

  5. RNA splicing - Wikipedia

    en.wikipedia.org/wiki/RNA_splicing

    RNA splicing is a process in molecular biology where a newly-made precursor messenger RNA (pre-mRNA) transcript is transformed into a mature messenger RNA ().It works by removing all the introns (non-coding regions of RNA) and splicing back together exons (coding regions).

  6. Group II intron - Wikipedia

    en.wikipedia.org/wiki/Group_II_intron

    Group II introns are found in rRNA, tRNA, and mRNA of organelles (chloroplasts and mitochondria) in fungi, plants, and protists, and also in mRNA in bacteria.The first intron to be identified as distinct from group I was the ai5γ group IIB intron, which was isolated in 1986 from a pre-mRNA transcript of the oxi 3 mitochondrial gene of Saccharomyces cerevisiae.

  7. Trans-splicing - Wikipedia

    en.wikipedia.org/wiki/Trans-splicing

    The signal for this splicing is the outron at the 5’ end of the mRNA, in the absence of a functional 5’ splice site upstream. When the 5’ outron in spliced, the 5’ splice site of the spliced leader RNA is branched to the outron and forms an intermediate. [10] This step results in a free spliced leader exon.

  8. AOL reviewed: This smart humidifier helps me sleep better in ...

    www.aol.com/lifestyle/levoit-dual-200s-smart...

    The Levoit Duual 200S Smart Humidifier is a compact and reasonably priced mister that can help maintain comfortable humidity levels in your home.

  9. Reel-to-reel audio tape recording - Wikipedia

    en.wikipedia.org/wiki/Reel-to-reel_audio_tape...

    Tape to be spliced is clamped in a splicing block attached to the deck near the heads to hold the tape accurately while the edit is made. The Editall was a long-in-production splicing block, named for its inventor Joe Tall, a tape editor at CBS. [6] Professional-style tape reel designed to fit large NARTB hub.