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  2. Chemiosmosis - Wikipedia

    en.wikipedia.org/wiki/Chemiosmosis

    A Proton Gradient Powers the Synthesis of ATP". Biochemistry (5th ed.). W. H. Freeman. A set of experiments aiming to test some tenets of the chemiosmotic theory – Ogawa S, Lee TM (August 1984). "The relation between the internal phosphorylation potential and the proton motive force in mitochondria during ATP synthesis and hydrolysis".

  3. Mitochondrial matrix - Wikipedia

    en.wikipedia.org/wiki/Mitochondrial_matrix

    The protons return to the mitochondrial matrix through the protein ATP synthase. The energy is used in order to rotate ATP synthase which facilitates the passage of a proton, producing ATP. A pH difference between the matrix and intermembrane space creates an electrochemical gradient by which ATP synthase can pass a proton into the matrix ...

  4. Electrochemical gradient - Wikipedia

    en.wikipedia.org/wiki/Electrochemical_gradient

    The proton gradient can be generated through either noncyclic or cyclic photophosphorylation. Of the proteins that participate in noncyclic photophosphorylation, photosystem II (PSII), plastiquinone, and cytochrome b 6 f complex directly contribute to generating the proton gradient. For each four photons absorbed by PSII, eight protons are ...

  5. Proton pump - Wikipedia

    en.wikipedia.org/wiki/Proton_pump

    In cell respiration, the proton pump uses energy to transport protons from the matrix of the mitochondrion to the inter-membrane space. [1] It is an active pump that generates a proton concentration gradient across the inner mitochondrial membrane, because there are more protons outside the matrix than inside.

  6. Mitochondrion - Wikipedia

    en.wikipedia.org/wiki/Mitochondrion

    This process is known as proton leak or mitochondrial uncoupling and is due to the facilitated diffusion of protons into the matrix. The process results in the unharnessed potential energy of the proton electrochemical gradient being released as heat. [21] The process is mediated by a proton channel called thermogenin, or UCP1. [49]

  7. Oxidative phosphorylation - Wikipedia

    en.wikipedia.org/wiki/Oxidative_phosphorylation

    The enzyme uses the energy stored in a proton gradient across a membrane to drive the synthesis of ATP from ADP and phosphate (P i). Estimates of the number of protons required to synthesize one ATP have ranged from three to four, [68] [69] with some suggesting cells can vary this ratio, to suit different conditions. [70]

  8. Electron transport chain - Wikipedia

    en.wikipedia.org/wiki/Electron_transport_chain

    The complex contains coordinated copper ions and several heme groups. At the same time, eight protons are removed from the mitochondrial matrix (although only four are translocated across the membrane), contributing to the proton gradient. The exact details of proton pumping in Complex IV are still under study. [9] Cyanide is an inhibitor of ...

  9. Uncoupling protein - Wikipedia

    en.wikipedia.org/wiki/Uncoupling_protein

    Structure of the human uncoupling protein UCP1. An uncoupling protein (UCP) is a mitochondrial inner membrane protein that is a regulated proton channel or transporter.An uncoupling protein is thus capable of dissipating the proton gradient generated by NADH-powered pumping of protons from the mitochondrial matrix to the mitochondrial intermembrane space.