Search results
Results From The WOW.Com Content Network
Methylergometrine is sometimes used for both prevention [6] and acute treatment [7] of migraine. It is an active metabolite of methysergide. [8] In the treatment of cluster headaches, methylergometrine has been initiated at a dose of 0.2 mg/day, rapidly increased to 0.2 mg three times per day, and increased to a maximum of 0.4 mg three times per day.
Labor and delivery is a sequential process that results in the birth of a fetus and placenta. It is dependent on maternal and fetal chemical signals to stimulate muscles in the uterus to contract and relax. Of such signals include prostaglandins [4] and oxytocin. [5]
Additionally, PGF 2α has been linked to being naturally involved in the process of labor. It has been seen that there are higher levels of PGF 2α in maternal fluid during labor when compared to at term. [4] This signifies that there is likely a biological use and significance to the production and secretion of PGF 2α in labor. Prostaglandin ...
Meta-analyses indicate that calcium-channel blockers and an oxytocin antagonist can delay delivery by 2–7 days, and β2-agonist drugs delay by 48 hours but carry more side effects. [ 95 ] [ 136 ] Magnesium sulfate does not appear to be useful to prevent preterm birth. [ 137 ]
Tocolytics are used in preterm labor, which refers to when a baby is born too early before 37 weeks of pregnancy. As preterm birth represents one of the leading causes of neonatal morbidity and mortality, the goal is to prevent neonatal morbidity and mortality through delaying delivery and increasing gestational age by gaining more time for other management strategies like corticosteroids ...
Ergonovine is listed as Table I precursors under the United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances, as possible precursor compound for LSD. [29] As an N -alkyl derivative of ergine, ergonovine is also covered by the Misuse of Drugs Act 1971 , effectively rendering it illegal in the United Kingdom .
Prostaglandin E 2 (PGE 2), also known as dinoprostone, is a naturally occurring prostaglandin with oxytocic properties that is used as a medication. [2] [3] [4] Dinoprostone is used in labor induction, bleeding after delivery, termination of pregnancy, and in newborn babies to keep the ductus arteriosus open.
Synthetic oxytocin, sold under the brand name Pitocin among others, is a medication made from the peptide oxytocin. [6] [7] As a medication, it is used to cause contraction of the uterus to start labor, increase the speed of labor, and to stop bleeding following delivery. [6]