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Hydrogel dressing is a medical dressing based on hydrogels, three-dimensional hydrophilic structure. [1] The insoluble hydrophilic structures absorb polar wound exudates and allow oxygen diffusion at the wound bed to accelerate healing. [2]
Self-healing hydrogels are a specialized type of polymer hydrogel.A hydrogel is a macromolecular polymer gel constructed of a network of crosslinked polymer chains. Hydrogels are synthesized from hydrophilic monomers by either chain or step growth, along with a functional crosslinker to promote network formation.
Hydrogels can be used as drug delivery vehicles, for transdermal application, ophthalmic drug delivery, [11] cancer treatment [12] or for wound dressing. [7] [13] As a type of water based formulation, hydrogels are generally less greasy and are easier to be removed than oil-based formulations like organogels. [6]
Hydrogels based on non-covalent interactions or dynamic covalent chemistry can exhibit self-healing properties after cutting or breaking. [137] Hydrogels that can fully fluidize followed by self-healing are of particular interest in biomedical engineering for the development of injectable hydrogels for tissue regeneration or 3D bioprinting inks ...
Chitosan is used within some wound dressings to decrease bleeding. [79] Upon contact with blood, the bandage becomes sticky, effectively sealing the laceration. [80] Chitosan hydrogel-based wound dressings have also been found useful as burn dressings, and for the treatment of chronic diabetic wounds and hydrofluoric acid burns. [3] [79]
A wound-healing application has been developed which employs a mat of single wall carbon nanotubes (SWNTs) coated in a monolayer of povidone-iodine. [ 24 ] Research has previously found that the polymer polyvinylpyrrolidone (PVP, povidone) can coil around individual carbon nanotubes to make them water-soluble.