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Vagus nerve stimulation (VNS) is a medical treatment that involves delivering electrical impulses to the vagus nerve. It is used as an add-on treatment for certain types of intractable epilepsy , cluster headaches, treatment-resistant depression and stroke rehabilitation.
The vagus nerve is also responsible for regulating inflammation in the body, via the inflammatory reflex. [7] Efferent vagus nerve fibers innervating the pharynx and back of the throat are responsible for the gag reflex. In addition, 5-HT 3 receptor-mediated afferent vagus stimulation in the gut due to gastroenteritis is a cause of vomiting. [8]
Stimulation of the efferent vagus nerve slows heart rate, induces gastrointestinal motility, and inhibits TNF production in spleen. [1] Stimulation of the efferent pathway of the vagus nerve releases acetylcholine, the neurotransmitter which interacts with the α7 subunit of the nicotinic AChR (α7 nAChR). nAChR is expressed on the cell ...
Joseph signed on and began using a non-invasive VNS device that delivers electrical stimulation to the vagus nerve through the ear, twice a day for 10 minutes at a time. The longest nerve in the ...
A vagal maneuver is an action used to stimulate the parasympathetic nervous system by activating the vagus nerve.The vagus nerve is the longest nerve of the autonomic nervous system and helps regulate many critical aspects of human physiology, including heart rate, blood pressure, sweating, and digestion through the release of acetylcholine.
Measurements of vagal tone can be performed by means of either invasive or noninvasive procedures. Invasive procedures are in the minority and include vagus nerve stimulation by specific manual, breathing or electrical techniques. Noninvasive techniques mainly rely on the investigation of heart rate and heart rate variability. [4] [5] [6]
Vagus nerve stimulation (VNS) [27] Hypoglossal nerve stimulation, an option for some patients who have obstructive sleep apnea [28] Percutaneous tibial nerve stimulation (PTNS) for the treatment of incontinence. Peripheral nerve stimulation (PNS, which refers to simulation of nerves beyond the spine or brain, and may be considered to include ...
This discovery that the vagus nerve controls the immune system led him to study the effects of stimulating the vagus nerve with electrodes to alleviate inflammation, called "the inflammatory reflex". [10] [11] [12] In 2007 he co-founded a company called SetPoint Medical which aimed to develop vagus nerve stimulation devices to treat autoimmune ...