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HIV-1 is more virulent and more infective than HIV-2, [20] and is the cause of the majority of HIV infections globally. The lower infectivity of HIV-2, compared to HIV-1, implies that fewer of those exposed to HIV-2 will be infected per exposure. Due to its relatively poor capacity for transmission, HIV-2 is largely confined to West Africa. [21]
Globally, the most common mode of HIV transmission is via sexual contacts between people of the opposite sex; [18] however, the pattern of transmission varies among countries. As of 2017 [update] , most HIV transmission in the United States occurred among men who had sex with men (82% of new HIV diagnoses among males aged 13 and older and 70% ...
The activation and proliferation of T cells that results from immune activation provides fresh targets for HIV infection. However, direct killing by HIV alone cannot account for the observed depletion of CD4 + T cells since only 0.01–0.10% of CD4 + T cells in the blood are infected. [citation needed]
Full contents of Understanding AIDS (PDF format) The pamphlet contains simple information about AIDS and HIV, and factual descriptions of how it is transmitted through sexual contact and drug use. It advocates for abstinence, monogamy, condom use, and sex education for young people. It encourages the reader not to fear day-to-day contact with ...
The two major modes of transmission to women are heterosexual sexual intercourse and intravenous drug use. [13] Women can transmit the HIV/AIDS virus to other women through sexual intercourse. [14] However, the U.S. does not statistically categorize HIV/AIDS transmission in forms other than heterosexual, intravenous drug, or indefinable ...
Based on these studies, the World Health Organization and UNAIDS both recommended male circumcision as a method of preventing female-to-male HIV transmission in 2007. [28] Whether it protects against male-to-female transmission is disputed [29] [30] and whether it is of benefit in developed countries and among men who have sex with men is ...
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