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Oral nevi or oral melanocytic nevi, are result of benign proliferations of nevus cells present either in the epithelial layer, the submucosal layer or both. Most commonly seen presentation of oral nevi are intramucosal nevi, these are dome shaped brown papules accounting for 64% of all reported case of oral nevi. [ 23 ]
White sponge nevus (WSN) is an extremely rare autosomal dominant [4] condition of the oral mucosa (the mucous membrane lining of the mouth). It is caused by one or more mutations in genes coding for keratin , which causes a defect in the normal process of keratinization of the mucosa.
An intramucosal nevus is a nevus within the mucosa as found in for example the mouth and genital areas. In the mouth, they are found most frequently on the hard palate. They are typically light brown and dome-shaped. [12] Intramucosal nevi account for 64% of all reported case of oral nevi. [13]
This stage begins the acute phase of noma. The telltale sign is facial edema (swelling) of the lips, cheeks, eyes, etc. Ulceration of the gums worsens during this stage; ulceration may spread to the mucosa (soft, mucus-producing tissue) of the mouth and nose. The patient may feel pain or soreness in their mouth and cheeks.
A melanocytic nevus (also known as nevocytic nevus, nevus-cell nevus, and commonly as a mole) [1] [2] is usually a noncancerous condition of pigment-producing skin cells. It is a type of melanocytic tumor that contains nevus cells . [ 2 ]
The ethnic variation may be explained by genetic factors or simply because dark skinned people have greater amount of melanin in the mucosa, making it appear darker (termed racial or physiologic pigmentation). This darker mucosa may make the edematous changes more noticeable, whereas in the mucosa of people with lighter skin types leukoedema ...
Verruciform xanthoma is an uncommon benign [1] lesion that has a verruciform (wart-like) appearance, but it may appear polypoid, papillomatous, or sessile. [2]: 535 The verruciform was first described by Shafer in 1971 on the oral mucosa. [3]
A port-wine stain (nevus flammeus) is a discoloration of the human skin caused by a vascular anomaly (a capillary malformation in the skin). [1] They are so named for their coloration, which is similar in color to port wine , a fortified red wine from Portugal .