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Schizophrenia is a mental disorder [17] [7] ... Many genes are known to be involved in schizophrenia, each with small effects and unknown transmission and expression.
The cumulative effects of pollution associated with the urban environment have been suggested as the link between urbanicity and the higher risk of developing schizophrenia. [ 169 ] Various possible explanations for the effect have been judged unlikely based on the nature of the findings, including infectious causes or a general stress effect.
A Cochrane review found limited evidence for its possible antipsychotic effects in the treatment of schizophrenia and called for more studies. [164] Another review found limited evidence for its use as an add-on therapy for the relief of symptoms but positive results were found for the treatment of sleep disorders that often accompany ...
These antipsychotic medications have adverse effects such as weight gain and induce feelings of fatigue that inhibit physical activity. The request for the people with schizophrenia to exercise for cardiovascular health then take medications (originally named "major tranquilizers") that inhibit activity is a double bind. [20] [21]
The glutamate hypothesis of schizophrenia models the subset of pathologic mechanisms of schizophrenia linked to glutamatergic signaling. The hypothesis was initially based on a set of clinical, neuropathological, and, later, genetic findings pointing at a hypofunction of glutamatergic signaling via NMDA receptors .
Visual processing abnormalities in schizophrenia are commonly found, and contribute to poor social function. [ 1 ] There is evidence that schizophrenia affects perception of contrast and motion , control of eye movements , detection of visual contours, and recognition of faces or facial expressions .
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