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  2. Cytochrome P450 - Wikipedia

    en.wikipedia.org/wiki/Cytochrome_P450

    The CYP nomenclature is the official naming convention, although occasionally CYP450 or CYP 450 is used synonymously. These names should never be used as according to the nomenclature convention (as they denote a P450 in family number 450).

  3. P450-containing systems - Wikipedia

    en.wikipedia.org/wiki/P450-containing_systems

    Any enzyme system that includes cytochrome P450 protein or domain can be called a P450-containing system. [1] [2] [3] [4]P450 enzymes usually function as a terminal oxidase in multicomponent electron-transfer chains, called P450-containing monooxygenase systems, although self-sufficient, non-monooxygenase P450s have been also described.

  4. Cytochrome P450 (individual enzymes) - Wikipedia

    en.wikipedia.org/wiki/Cytochrome_P450...

    Cytochrome P450 aromatic O-demethylase, which is made of two distinct promiscuous parts: a cytochrome P450 protein (GcoA) and three domain reductase, is significant for its ability to convert Lignin, the aromatic biopolymer common in plant cell walls, into renewable carbon chains in a catabolic set of reactions. In short, it is a facilitator of ...

  5. List of cytochrome P450 modulators - Wikipedia

    en.wikipedia.org/wiki/List_of_cytochrome_P450...

    This is a list of cytochrome P450 modulators, or inhibitors and inducers of cytochrome P450 enzymes. Enzyme Inhibitors Inducers; CYP1A1: Certain foods (e.g., cumin ...

  6. CYP3A4 - Wikipedia

    en.wikipedia.org/wiki/CYP3A4

    Cytochrome P450 3A4 (abbreviated CYP3A4) (EC 1.14.13.97) is an important enzyme in the body, mainly found in the liver and in the intestine, which in humans is encoded by CYP3A4 gene. It oxidizes small foreign organic molecules ( xenobiotics ), such as toxins or drugs, so that they can be removed from the body.

  7. Cytochrome P450 engineering - Wikipedia

    en.wikipedia.org/wiki/Cytochrome_P450_engineering

    P450 BM3 (also known as CYP102A1) is a cytochrome P450 enzyme isolated from Bacillus megaterium. [2] [4] [5] [6] [8] BM3 has been extensively studied in the context of enzyme engineering due to its solubility, tractable bacterial isoforms and self-sufficient electron transport system, but also due to its synthetic utility. [8]

  8. CYP2E1 - Wikipedia

    en.wikipedia.org/wiki/CYP2E1

    Cytochrome P450 2E1 (abbreviated CYP2E1, EC 1.14.13.n7) is a member of the cytochrome P450 mixed-function oxidase system, which is involved in the metabolism of xenobiotics in the body. This class of enzymes is divided up into a number of subcategories, including CYP1, CYP2, and CYP3, which as a group are largely responsible for the breakdown ...

  9. CYP2B6 - Wikipedia

    en.wikipedia.org/wiki/CYP2B6

    Cytochrome P450 2B6 is an enzyme that in humans is encoded by the CYP2B6 gene. [5] CYP2B6 is a member of the cytochrome P450 group of enzymes. Along with CYP2A6 , it is involved with metabolizing nicotine , along with many other substances.