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List of Antiviral Drugs Antiviral Use Manufacturer Component Type Year approved Abacavir: HIV: ViiV Healthcare: Nucleoside analogue reverse transcriptase inhibitor (NRTI) 1998 Acyclovir (Aciclovir) Herpes Simplex, chickenpox, [2] varicella zoster virus: GSK: guanosine analogue RTI 1981 Adefovir: Hepatitis B [3] Gilead Sciences RTI 2002 , 2003 ...
Most of the antiviral drugs now available are designed to help deal with HIV, herpes viruses, the hepatitis B and C viruses, and influenza A and B viruses. [ 6 ] Viruses use the host's cells to replicate and this makes it difficult to find targets for the drug that would interfere with the virus without also harming the host organism's cells.
Some of the most well known are antiviral drugs widely used to treat HIV/AIDS, hepatitis C and COVID-19. These protease inhibitors prevent viral replication by selectively binding to viral proteases (e.g. HIV-1 protease ) and blocking proteolytic cleavage of protein precursors that are necessary for the production of infectious viral particles .
Hepatitis A is an infectious disease of the liver caused by Hepatovirus A (HAV); [7] it is a type of viral hepatitis. [8] Many cases have few or no symptoms, especially in the young. [ 1 ] The time between infection and symptoms, in those who develop them, is two–six weeks. [ 2 ]
entecavir (hepatitis B) ribavirin; thymidine and deoxythymidine analogues: stavudine (d4T) telbivudine (hepatitis B) zidovudine (azidothymidine, or AZT)(HIV) deoxyuridine analogues: idoxuridine; trifluridine; Related drugs are nucleobase analogs, which don't include a sugar or sugar analog, and nucleotide analogues, which also include phosphate ...
Ritonavir is indicated in combination with other antiretroviral agents for the treatment of HIV-1-infected patients. [4] [5] [8] Though initially developed as an independent antiviral treatment, it is most commonly used as a pharmacokinetic enhancer, in order to increase the plasma concentrations of other antiretrovirals.