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Nicotine is a secondary metabolite produced in a variety of plants in the family Solanaceae, most notably in tobacco Nicotiana tabacum, where it can be found at high concentrations of 0.5 to 7.5%. [178] Nicotine is also found in the leaves of other tobacco species, such as Nicotiana rustica (in amounts of 2–14%).
Zyn pouches are sold in round cans containing 15 or 20 pouches depending on the market. Pouches are available in different levels of nicotine strength (such as 3 or 6 milligrams per pouch in the US) and different flavored and unflavored varieties. [17] The pouches contain nicotine extracted from tobacco leaves, and food grade ingredients. [18]
The LD 50 of nicotine is 50 mg/kg for rats and 3 mg/kg for mice. 0.5–1.0 mg/kg can be a lethal dosage for adult humans, and 0.1 mg/kg for children. [19] [20] However the widely used human LD 50 estimate of 0.5–1.0 mg/kg was questioned in a 2013 review, in light of several documented cases of humans surviving much higher doses; the 2013 review suggests that the lower limit causing fatal ...
A nicotine base and a weak acid such as benzoic acid or levulinic acid is used to form a nicotine salt. [1] Across a sample of 23 nicotine salts available for public purchase, the three most common acids used in the formation of nicotine salts were lactic acid, benzoic acid and levulinic acid. [8]
Nicotiana rustica, commonly known as Aztec tobacco [2] or strong tobacco, [3] is a rainforest plant in the family Solanaceae native to South America.It is a very potent variety of tobacco, containing up to nine times more nicotine than common species of Nicotiana such as Nicotiana tabacum (common tobacco). [4]
Bridging the gap between cigars and cigarettes, More was the first successful 120 mm cigarette. It had a strong flavor and when introduced was higher in tar and nicotine than most filter cigarettes on the market. It is sold in both the full flavor and menthol flavors.