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Chemotherapy-induced acral erythema, also known as palmar-plantar erythrodysesthesia or hand-foot syndrome is reddening, swelling, numbness and desquamation (skin sloughing or peeling) on palms of the hands and soles of the feet (and, occasionally, on the knees, elbows, and elsewhere) that can occur after chemotherapy in patients with cancer.
Since acral lentiginous melanoma is not linked to sun or UV exposure and the cause is not well-understood, there are no specific preventative measures. [7] However, Patient education can be geared towards populations in which ALM is more common to increase awareness of the warning signs of ALM and other melanomas to help with earlier detection ...
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. [3] [4] Cancer can be difficult to diagnose because its signs and symptoms are often nonspecific, meaning they may be general phenomena that do not point directly to a specific disease process.
Lung cancer is more frequent if the tripe palms present alone, whereas cancer of the stomach is more frequent when AN is also present. [1] The sign has also been associated with bullous pemphigoid, psoriasis, and exfoliative dermatitis. [2] It is believed that growth factors secreted by cancer cells cause some skin cells to grow. [3]
Glomus tumors are usually solitary and small lesions. The vast majority are found in the hand, wrist, foot, and under the fingernails. [3] They are often painful, and the pain is reproduced when the lesion is placed in cold water - a history of sensitivity to cold weather is also common. [6] Multiple tumors are less likely to be painful.
Cutaneous squamous-cell carcinoma (cSCC), also known as squamous-cell carcinoma of the skin or squamous-cell skin cancer, is one of the three principal types of skin cancer, alongside basal-cell carcinoma and melanoma. [10] cSCC typically presents as a hard lump with a scaly surface, though it may also present as an ulcer. [1]
Symptoms can range from looking like a pimple that doesn’t heal to a shiny, skin-colored bump, a white or waxy lesion, a flat, scaly patch or a lesion that is black, brown or blue.
Epidermodysplasia verruciformis (EV) is a skin condition characterised by warty skin lesions. [1] It results from an abnormal susceptibility to HPV infection (HPV). It is associated with a high lifetime risk of squamous cell carcinomas in skin. [1]