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Reperfusion therapy is a medical treatment to restore blood flow, either through or around, blocked arteries, typically after a heart attack (myocardial infarction (MI)). Reperfusion therapy includes drugs and surgery .
The main reason for the acute phase of ischemia-reperfusion injury is oxygen deprivation and, therefore, arrest of generation of ATP (cellular energy currency) by mitochondria oxidative phosphorylation. Tissue damage due to the general energy deficit during ischemia is followed by reperfusion (increase of oxygen level) when the injury is enhanced.
The patients cannula are attached to an ECMO circuit with blood flow targets of 3Lmin −1 and oxygen blood flow of 3L min −1 commenced. An arterial blood gas is used to assess for successful oxygenation and metabolic improvement following the commencement of ECMO.
Extracorporeal membrane oxygenation (ECMO), is a form of extracorporeal life support, providing prolonged cardiac and respiratory support to persons whose heart and lungs are unable to provide an adequate amount of oxygen, gas exchange or blood supply to sustain life.
Reperfusion is the restoration of blood flow to an organ or tissue after having been blocked, and may refer to: Reperfusion injury , tissue damage caused when blood supply returns to the tissue Reperfusion therapy , the medical treatment that restores blood flow through blocked arteries, typically after a heart attack
The cannula used to return oxygenated blood is usually inserted in the ascending aorta, but there is a possibility that it is inserted in the femoral artery, axillary artery, or brachiocephalic artery according to the demand of the surgery. [10] [20] After the cannula is inserted, venous blood is drained from the body by the cannula into a ...
Heated humidified high-flow therapy, often simply called high flow therapy, is a medical treatment providing respiratory support by delivering a flow of oxygen of up to 60 liters per minute to a patient through a large-bore or high-flow nasal cannula. Primarily studied in neonates, it has also been found effective in some adults to treat ...
The most common form of venous access is a peripheral venous cannula which is generally inserted into veins of the hands, forearms, and occasionally feet. [1] Healthcare providers may use a number of different techniques in order to improve the chances of successful access.