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  2. Systemic disease - Wikipedia

    en.wikipedia.org/wiki/Systemic_disease

    Almost any part of the eye can give important clues to the diagnosis of systemic diseases. Signs of a systemic disease may be evident on the outer surface of the eye (eyelids, conjunctiva and cornea), middle of the eye and at the back of the eye (retina)." [4] Since 500 B.C., some researchers have believed that the physical condition of the ...

  3. Necrosis - Wikipedia

    en.wikipedia.org/wiki/Necrosis

    Low oxygen conditions, such as those common in blind mole rats' burrows, usually cause cells to undergo apoptosis. In adaptation to higher tendency of cell death, blind mole rats evolved a mutation in the tumor suppressor protein p53 (which is also used in humans) to prevent cells from undergoing apoptosis. Human cancer patients have similar ...

  4. Systemic inflammation - Wikipedia

    en.wikipedia.org/wiki/Systemic_inflammation

    Chronic systemic inflammation is the result of release of pro-inflammatory cytokines from immune-related cells and the chronic activation of the innate immune system.It can contribute to the development or progression of certain conditions such as cardiovascular disease, cancer, diabetes mellitus, chronic kidney disease, non-alcoholic fatty liver disease, autoimmune and neurodegenerative ...

  5. Immune system - Wikipedia

    en.wikipedia.org/wiki/Immune_system

    The cells of the adaptive immune system are special types of leukocytes, called lymphocytes. B cells and T cells are the major types of lymphocytes and are derived from hematopoietic stem cells in the bone marrow. [57] B cells are involved in the humoral immune response, whereas T cells are involved in cell-mediated immune response.

  6. Mitotic catastrophe - Wikipedia

    en.wikipedia.org/wiki/Mitotic_catastrophe

    A cell that has been treated with taxol and had a catastrophic mitosis. The cell has become multinucleated after an unsuccessful mitosis. Mitotic catastrophe has been defined as either a cellular mechanism to prevent potentially cancerous cells from proliferating or as a mode of cellular death that occurs following improper cell cycle progression or entrance.

  7. Could the FDA's recently approved Pap smear alternative ... - AOL

    www.aol.com/could-fdas-recently-approved-pap...

    Around 11,500 Americans are diagnosed with cervical cancer each year, according to data from the Centers for Disease Control and Prevention, and in 2022, over 4,000 people died from the disease ...

  8. Anticancer gene - Wikipedia

    en.wikipedia.org/wiki/Anticancer_gene

    Cancer is a group of diseases where cells multiply uncontrollably. [1] Normally, cells have a built-in process called apoptosis that triggers cell death to prevent excessive growth. However, when these processes are disrupted, cancer can develop. Studies show that cancer is one of the leading causes of death worldwide. [1]

  9. Cancer immunotherapy - Wikipedia

    en.wikipedia.org/wiki/Cancer_immunotherapy

    An oncolytic virus is a virus that preferentially infects and kills cancer cells. As the infected cancer cells are destroyed by oncolysis, they release new infectious virus particles or virions to help destroy the remaining tumour. Oncolytic viruses are thought not only to cause direct destruction of the tumour cells, but also to stimulate host ...