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Like any injection, cortisone shots come with the risk of infection. Additionally, they may cause side effects such as increased blood sugar levels, skin thinning, or changes in pigmentation ...
Cortisone is a pregnene (21-carbon) steroid hormone.It is a naturally-occurring corticosteroid metabolite that is also used as a pharmaceutical prodrug. Cortisol is converted by the action of the enzyme corticosteroid 11-beta-dehydrogenase isozyme 2 into the inactive metabolite cortisone, particularly in the kidneys.
In osteoarthritis, joint injection of glucocorticoids (such as hydrocortisone) leads to short term pain relief that may last between a few weeks and a few months. [5] Injections of hyaluronic acid have not produced improvement compared to placebo for knee arthritis, [6] [7] but did increase risk of further pain. [6]
Dr. Carrie Jose, in her latest Health and Wellness column, provides questions to ask before getting a cortisone injection
The most common side effects from this procedure include itching, rash, nausea, facial flushing/sweating. [10] Some patients experience temporary weight gain due to the steroid. Diabetics may experience an increase in blood sugar. [10] [4] This is a quick and simple procedure, so complications are very rare, but should not be ignored. The risk ...
Serious side effects include iatrogenic Cushing's syndrome, hypertension, osteoporosis, diabetes, infection, and skin atrophy. [9] Chemically, methylprednisolone is a synthetic pregnane steroid hormone derived from hydrocortisone and prednisolone. It belongs to a class of synthetic glucocorticoids and more generally, corticosteroids. It acts as ...