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The benzimidazole compounds albendazole (brand names e.g., Albenza, Eskazole, Zentel and Andazol) and mebendazole (brand names e.g., Ovex, Vermox, Antiox and Pripsen) are the most effective. [26] They work by inhibiting the microtubule function in the pinworm adults, causing glycogen depletion, [ 26 ] thereby effectively starving the parasite ...
Mebendazole has a much higher failure rate in clinical practice than albendazole or ivermectin. [25] However, these drugs have little effect on the autoinfective larvae. Hence, repeat treatments with ivermectin or albendazole must be administered to kill newly matured parasites that have developed from the autoinfective larvae.
Albendazole is a broad-spectrum antihelmintic and antiprotozoal agent of the benzimidazole type. [3] It is used for the treatment of a variety of intestinal parasite infections, including ascariasis, pinworm infection, hookworm infection, trichuriasis, strongyloidiasis, taeniasis, clonorchiasis, opisthorchiasis, cutaneous larva migrans, giardiasis, and gnathostomiasis, among other diseases.
Single-dose of albendazole, mebendazole, and ivermectin are effective against ascariasis. They are effective at removing parasites and eggs from the intestines. [35] Other effective agents include tribendimidine and nitazoxanide. [2] Pyrantel pamoate may induce intestinal obstruction in a heavy worm load.
Mebendazole (MBZ), sold under the brand name Vermox among others, is a medication used to treat a number of parasitic worm infestations. [5] This includes ascariasis , pinworm infection , hookworm infections , guinea worm infections and hydatid disease , among others. [ 5 ]
Albendazole – effective against threadworms, roundworms, whipworms, tapeworms, hookworms; Mebendazole – effective against various nematodes; Thiabendazole – effective against various nematodes; Fenbendazole – effective against various parasites; Triclabendazole – effective against liver flukes; Flubendazole – effective against most ...
An expanding coalition of health and consumer advocates is campaigning against Robert F. Kennedy Jr.'s nomination to the top U.S. health job over concerns about his activism against vaccines and ...
A 2008 review found that the efficacy of single-dose treatments for hookworm infections were as follows: 72% for albendazole, 15% for mebendazole, and 31% for pyrantel pamoate. [29] This substantiates prior claims that albendazole is much more effective than mebendazole for hookworm infections.