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Cytomegalovirus retinitis, also known as CMV retinitis, is an inflammation of the retina of the eye that can lead to blindness. [1] Caused by human cytomegalovirus , it occurs predominantly in people whose immune system has been compromised, including 15-40% of those with AIDS.
The CMV pp65 assay is widely used for monitoring CMV infection and its response to antiviral treatment in people who are under immunosuppressive therapy and have had renal transplantation surgery, as the antigenemia results are obtained about 5 days before the onset of symptomatic CMV disease.
Treatment for CMV infection should start at 1 month of age and should occur for 6 months. The options for treatment are intravenous ganciclovir and oral valganciclovir. After diagnosis, it is important to further investigate any possible evidence of end-organ disease and symptoms through blood tests, imaging, ophthalmology tests, and hearing tests.
HIV PI 1996 Lamivudine: HIV cytidine analogue RTI Letermovir (Prevymis) [12] Cytomegalovirus (CMV) Lopinavir: HIV Loviride: HIV Maraviroc: HIV entry inhibitor: Methisazone: Smallpox: Molnupiravir: COVID-19: Merck & Co. viral RNA polymerase inhibitor Moroxydine: Influenza Nelfinavir: HIV Nirmatrelvir/ritonavir (Paxlovid) COVID-19: Pfizer
In summary, as the WHO HIV treatment guidelines state, "The ARV regimens now available, even in the poorest countries, are safer, simpler, more effective and more affordable than ever before." [44] There is a consensus among experts that, once initiated, antiretroviral therapy should never be stopped.
Cytomegalovirus (CMV) (from cyto-'cell' via Greek κύτος kútos - 'container' + μέγας mégas 'big, megalo-' + -virus via Latin vīrus 'poison') is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, [3] in the subfamily Betaherpesvirinae. Humans and other primates serve as natural hosts.
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