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However, these cells did not self-renew and were subsequently depleted as they generated new neurons, thus failing to satisfy the requirement for stem cells. [6] [7] One study observed that ependymal cells from the lining of the lateral ventricle might be a source for cells which can be transplanted into the cochlea to reverse hearing loss. [8]
This schematic illustrates the four different types of glial cells, all of which possess cytoplasmic processes: ependymal cells (light pink), astrocytes (green), microglia (red), and oligodendrocytes (light blue). Cell bodies of neurons are in yellow (Their axons are surrounded by myelin, produced by oligodendrocytes).
Ependymomas are composed of cells with regular, round to oval nuclei. There is a variably dense fibrillary background. Tumor cells may form gland-like round or elongated structures that resemble the embryologic ependymal canal, with long, delicate processes extending into the lumen; more frequently present are perivascular pseudorosettes in which tumor cells are arranged around vessels with an ...
The tela choroidea (or tela chorioidea) is a region of meningeal pia mater that adheres to the underlying ependyma, and gives rise to the choroid plexus in each of the brain’s four ventricles.
The central canal (also known as spinal foramen or ependymal canal) is the cerebrospinal fluid-filled space that runs through the spinal cord. [1] The central canal lies below and is connected to the ventricular system of the brain , from which it receives cerebrospinal fluid, and shares the same ependymal lining.
Ependymal cells: Ependymal cells, also named ependymocytes, line the spinal cord and the ventricular system of the brain. These cells are involved in the creation and secretion of cerebrospinal fluid (CSF) and beat their cilia to help circulate the CSF and make up the blood-CSF barrier. They are also thought to act as neural stem cells. [15] CNS
These form the ventricular system of the brain: [8] The neural stem cells of the developing brain, principally radial glial cells, line the developing ventricular system in a transient zone called the ventricular zone. [9] The prosencephalon divides into the telencephalon, which forms the cortex of the developed brain, and the diencephalon.
Moving away from the ependymal layer of the SVZ the neural cells become more and more differentiated. In the adult CNS, neuroepithelial cells arise in several different areas of the brain: the subventricular zone (SVZ), the olfactory bulb and the dentate gyrus of the hippocampus. These cells do not appear in any of the peripheral nervous system.