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  2. Daratumumab - Wikipedia

    en.wikipedia.org/wiki/Daratumumab

    [34] [35] In May 2016 daratumumab was also conditionally approved by the European Medicines Agency for treatment of multiple myeloma. [36] In November 2016, the FDA approved daratumumab in combination with lenalidomide or bortezomib and dexamethasone for the treatment of people with multiple myeloma who have received at least one prior therapy ...

  3. Daratumumab/hyaluronidase - Wikipedia

    en.wikipedia.org/wiki/Daratumumab/hyaluronidase

    It was approved for use in the United States in May 2020. [2] [7] [8]Efficacy of daratumumab and hyaluronidase-fihji (monotherapy) was evaluated in the COLUMBA trial (NCT03277105), an open-label non-inferiority trial randomizing 263 participants to daratumumab and hyaluronidase-fihj and 259 to intravenous daratumumab (daratumumab IV). [2]

  4. Hyaluronidase - Wikipedia

    en.wikipedia.org/wiki/Hyaluronidase

    In July 2021, the U.S. Food and Drug Administration (FDA) approved daratumumab and hyaluronidase-fihj in combination with pomalidomide and dexamethasone for adults with multiple myeloma who have received at least one prior line of therapy including lenalidomide and a proteasome inhibitor. [36]

  5. GSK's Sinus Disease Drug Secures Approval In China - AOL

    www.aol.com/gsks-sinus-disease-drug-secures...

    The FDA approved Nucala for the same indication in July 2021. This is the third indication for mepolizumab in China for an IL-5 mediated condition. It is estim. On Friday, the China National ...

  6. GSK's asthma drug Nucala meets main goal in study on ... - AOL

    www.aol.com/news/gsks-asthma-drug-nucala-meets...

    Nucala, known also as mepolizumab, was first approved in 2015 for a type of severe asthma in the United States. Its sales grew 18% to 1.7 billion pounds in 2023. It contributed nearly 6% to GSK ...

  7. Pharma Stock Roundup: FDA Panel's Nod to PFE/BNTX ... - AOL

    www.aol.com/news/pharma-stock-roundup-fda-panels...

    An FDA panel recommends granting approval for emergency use of Pfizer's (PFE) COVID-19 vaccine. Glaxo (GSK)/Sanofi (SNY) COVID-19 vaccine plan delays.

  8. Belantamab mafodotin - Wikipedia

    en.wikipedia.org/wiki/Belantamab_mafodotin

    In November 2022, GSK plc initiated the process for withdrawal of the United States marketing authorization for belantamab mafodotin following the request of the US FDA. [9] This request was based on the outcome of the DREAMM-3 phase III confirmatory trial, [10] which did not meet the requirements of the US FDA accelerated approval regulations ...

  9. List of drugs granted breakthrough therapy designation

    en.wikipedia.org/wiki/List_of_drugs_granted...

    In combination with palbociclib and fulvestrant for the treatment of adults with endocrine-resistant, PIK3CA-mutated, hormone receptor (HR)-positive, human epidermal growth-factor receptor 2 (HER2)-negative, locally advanced or metastatic breast cancer, as detected by an FDA-approved test, following recurrence on or after completing adjuvant ...

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