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Skin grafting, a type of graft surgery, involves the transplantation of skin without a defined circulation. The transplanted tissue is called a skin graft. [1] Surgeons may use skin grafting to treat: extensive wounding or trauma; burns; areas of extensive skin loss due to infection such as necrotizing fasciitis or purpura fulminans [2]
The use of this particular animal's skin is 'unprecedented,' according to one professor involved with the research.
Kerecis is an Icelandic company that uses fish skins to treat wounds. [3] [4] The decellularized skin of the Atlantic cod is used as a graft, which increases the elasticity, tensile strength, and compressibility of the wound. [5] Kerecis has subsidiaries in Switzerland and the United States. [6] It is based in Ísafjörður, Iceland. [7] [8]
FTSGs are the most frequently used grafts in dermatology, [14] which involves surgical removal of the epidermis and dermis layers of the skin. After the skin graft is harvested, the donor site is stitched close, and the graft is trimmed of any underlying hair or fat tissue, as well as contoured to match the size and shape of the defect. [15]
In one case, however, a particular type of collagen graft led to significant delay of wound closure. [6] Careful study of histology samples revealed that grafts that delayed wound closure induced the synthesis of new dermis de novo at the injury site, instead of forming scar, which is the normal outcome of the spontaneous wound healing response.
Keeled scales of a colubrid snake (banded water snake; Nerodia fasciata). In zoology, a scale (Ancient Greek: λεπίς, romanized: lepís; Latin: squāma) is a small rigid plate that grows out of an animal's skin to provide protection.
A fish scale is a small rigid plate that grows out of the skin of a fish. The skin of most jawed fishes is covered with these protective scales, which can also provide effective camouflage through the use of reflection and colouration, as well as possible hydrodynamic advantages.
Ichthyosis (also named fish scale disease) [1] is a family of genetic skin disorders characterized by dry, thickened, scaly skin. [2] The more than 20 types of ichthyosis range in severity of symptoms, outward appearance, underlying genetic cause and mode of inheritance (e.g., dominant, recessive , autosomal or X-linked ). [ 3 ]
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