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Stimulant use disorder is a type of substance use disorder where the use of stimulants caused clinically significant impairment or distress. It is defined in the DSM-5 as "the continued use of amphetamine -type substances, cocaine , or other stimulants leading to clinically significant impairment or distress, from mild to severe". [ 1 ]
Stimulants (also known as central nervous system stimulants, or psychostimulants, or colloquially as uppers) are a class of drugs that increase alertness. They are used for various purposes, such as enhancing attention , motivation , cognition , mood , and physical performance .
Stimulant psychosis is a mental disorder characterized by psychotic symptoms such as hallucinations, paranoid ideation, delusions, disorganized thinking, and grossly disorganized behaviour. It typically occurs following an overdose or several day binge on psychostimulants , [ 1 ] although it can occur in the course of stimulant therapy ...
People treated with stimulants such as methylphenidate during childhood were less likely to have substance use disorders in adulthood. [ 210 ] Among countries with the highest rates of use of methylphenidate medication is Iceland, [ 211 ] where research shows that the drug was the most commonly used substance among people who inject drugs . [ 212 ]
Amphetamine use is rising among students due to the ability to easily access prescribed stimulants like Adderall. [5] Also, in case of chronic use, vegetative disorders soon occur such as bouts of sweating, trouble sleeping , tremor , ataxia and diarrhea ; the degradation of the personality takes place relatively slowly.
Substance-related disorders are found to have greatest prevalence in individuals ages 18–25, with a higher likelihood occurring in men compared to women, and urban residents compared to rural residents. On average, general medical facilities hold 22% of patients with substance-related disorders, possibly leading to psychiatric disorders later on.
Amphetamine type stimulants can be used in the treatment of narcolepsy, a rare neurological disorder where the brain is unable to regulate the sleep-wake mechanism. [17] Amphetamines causes an increase in dopamine release, which is the proposed mechanism for its wake-promoting effect. [ 18 ]
The stimulants are the first line of treatment for ADHD, with proven efficacy, but they do fail in up to 20% of cases, even in patients without tic disorders. [271] Current prescribed stimulant medications include: methylphenidate, dextroamphetamine, and mixed amphetamine salts . Other medications can be used when stimulants are not an option.