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  2. Aliskiren - Wikipedia

    en.wikipedia.org/wiki/Aliskiren

    Aliskiren (brand names Tekturna and Rasilez) is the first in a class of drugs called direct renin inhibitors. It is used for essential (primary) hypertension . [ 2 ] While used for high blood pressure, other better studied medications are typically recommended due to concerns of higher side effects and less evidence of benefit.

  3. Aliskiren/hydrochlorothiazide - Wikipedia

    en.wikipedia.org/wiki/Aliskiren/hydrochlorothiazide

    Aliskiren/hydrochlorothiazide, sold under the brand name Tekturna HCT among others, is a fixed-dose combination medication for the treatment of hypertension ...

  4. Renin inhibitor - Wikipedia

    en.wikipedia.org/wiki/Renin_inhibitor

    Aliskiren, the third-generation renin inhibitor. Aliskiren, an orally active non-peptide renin inhibitor, was the first drug in its class on the market. It is used to treat hypertension as monotherapy or in combination with other antihypertensive agents. [7] [39] The key to the discovery of aliskiren was crystallography and molecular modeling ...

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  6. Antihypertensive - Wikipedia

    en.wikipedia.org/wiki/Antihypertensive

    Women are often concerned about the safety of antihypertensives and as a result, many do not take their treatment as prescribed. Shared decision-making aids have been shown to reduce women's uncertainty about taking antihypertensives and increase the number of women taking them as prescribed.

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  9. Aliskiren/amlodipine/hydrochlorothiazide - Wikipedia

    en.wikipedia.org/wiki/Aliskiren/amlodipine/...

    [1] [2] It contains aliskiren, a renin inhibitor; amlodipine, as the besylate, a calcium channel blocker; and hydrochlorothiazide, a thiazide diuretic. [1] It is taken by mouth. [1] It was approved for medical use in the United States in December 2010. [1] [3] [4] Amturnide was withdrawn by Novartis from the US market in 2017. [5]