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2. Alcohol withdrawal syndrome - Wikipedia

   en.wikipedia.org/wiki/Alcohol_withdrawal_syndrome

   During acute alcohol withdrawal, changes also occur such as upregulation of alpha4 containing GABA A receptors and downregulation of alpha1 and alpha3 containing GABA A receptors. Neurochemical changes occurring during alcohol withdrawal can be minimized with drugs which are used for acute detoxification.

3. Alcohol detoxification - Wikipedia

   en.wikipedia.org/wiki/Alcohol_detoxification

   Alcohol detoxification (also known as detox) is the abrupt cessation of alcohol intake in individuals that have alcohol use disorder. This process is often coupled with substitution of drugs that have effects similar to the effects of alcohol in order to lessen the symptoms of alcohol withdrawal .

4. Glossary of alcohol (drug) terms - Wikipedia

   en.wikipedia.org/wiki/Glossary_of_alcohol_(drug...

   Alcohol detoxification (also known as detox) is the abrupt cessation of alcohol intake in individuals that have alcohol use disorder. This process is often coupled with substitution of drugs that have effects similar to the effects of alcohol in order to lessen the symptoms of alcohol withdrawal.

5. Kindling (sedative–hypnotic withdrawal) - Wikipedia

   en.wikipedia.org/wiki/Kindling_(sedative...

   Failure to manage the alcohol withdrawal syndrome appropriately can lead to permanent brain damage or death. [11] Acamprosate, a drug used to promote abstinence from alcohol, an NMDA antagonist drug, reduces excessive glutamate activity in the central nervous system and thereby may reduce excitotoxicity and withdrawal related brain damage. [12 ...

6. Alcohol (drug) - Wikipedia

   en.wikipedia.org/wiki/Alcohol_(drug)

   Discontinuation of alcohol after extended heavy use and associated tolerance development (resulting in dependence) can result in withdrawal. Alcohol withdrawal can cause confusion, paranoia, anxiety, insomnia, agitation, tremors, fever, nausea, vomiting, autonomic dysfunction, seizures, and hallucinations. In severe cases, death can result.

7. Post-acute-withdrawal syndrome - Wikipedia

   en.wikipedia.org/wiki/Post-acute-withdrawal_syndrome

   Drug use, including alcohol and prescription drugs, can induce symptomatology which resembles mental illness. This can occur both in the intoxicated state and during the withdrawal state. In some cases these substance-induced psychiatric disorders can persist long after detoxification from amphetamine, cocaine, opioid, and alcohol use, causing ...