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[9] [10] Overdose of only a small number of capsules can be fatal. [10] Chewing or sucking on the capsule, releasing the drug into the mouth, can also lead to laryngospasm, bronchospasm, and circulatory collapse. [7] It is unclear if use in pregnancy or breastfeeding is safe. [11] Benzonatate is a local anesthetic and voltage-gated sodium ...
Dibunate is a cough suppressant. [1] As the sodium salt, it has been marketed under the name Becantyl (in the United Kingdom), Becantex (in continental Europe), or Linctussal with a dosage of 20 to 30 mg, as either syrup or tablets.
However, it is confusing when referring benzonatate as the only "non-narcotic antitussive" because narcotic in the Greek sense could refer to diphenhydramine (or Benadryl) which can be used for cough and is significantly sedating. Given all of this, it seems the best term for benzonatate would be "non-opioid antitussive" to avoid this confusion.
Antitussives, or cough suppressants, are substances which suppress the coughing itself. Examples are dextromethorphan, benzonatate, codeine, hydrocodone, pholcodine, noscapine, cloperastine, and butamirate. Antihistamines, for allergic rhinitis, may produce mild sedation and reduce other associated symptoms, like a runny nose and watery eyes.
The usual dosage of etifoxine (as the hydrochloride salt) is 150 to 200 mg per day in divided doses of 50 to 100 mg two to three times per day (e.g., 50 mg–50 mg–100 mg). [ 2 ] [ 7 ] [ 6 ] [ 18 ] [ 1 ] [ 19 ] [ 20 ] It is taken for a few days to a few weeks, but no longer than 12 weeks.
The drug acts as an antagonist at muscarinic receptors [3] (subtype M 1) and as an agonist at sigma receptors (subtype σ 1) [6] with an IC 50 of 9 nM. [10] Its anticholinergic properties can theoretically relax the pulmonary alveoli and reduce phlegm production. Spasmolytic and local anaesthetic properties have also been described. [5]
The Brigadier General Thomas F. Barr Award, first issued in 2009, is annually awarded to the all-around best Military Police unit of company-size or smaller "attached to, or supporting" the United States Army Corrections Command. According to the U.S. Army, the "award is intended to promote professionalism and esprit de corps by recognizing the ...
Pipazetate (INN Tooltip International Nonproprietary Name) (brand names Dipect, Lenopect, Selvigon, Theratuss, Toraxan), or pipazethate (USAN Tooltip United States Adopted Name), is a 1-azaphenothiazine drug that was briefly marketed as a cough suppressant.