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The proportion of AST to ALT in hepatocytes is about 2.5:1, but because AST is removed from serum by the liver sinusoidal cells twice as quickly (serum half-life t 1/2 = 18 hr) compared to ALT (t 1/2 = 36 hr), so the resulting serum levels of AST and ALT are about equal in healthy individuals, resulting in a normal AST/ALT ratio around 1.
A high gradient (> 1.1 g/dL, >11 g/L) indicates the ascites is due to portal hypertension, either liver related or non-liver related, with approximately 97% accuracy. [2] This is due to increased hydrostatic pressure within the blood vessels of the hepatic portal system , which in turn forces water into the peritoneal cavity but leaves proteins ...
In alcoholic liver disease, the mean ratio is 1.45, and mean ratio is 1.33 in post necrotic liver cirrhosis. Ratio is greater than 1.17 in viral cirrhosis, greater than 2.0 in alcoholic hepatitis, and 0.9 in non-alcoholic hepatitis. Ratio is greater than 4.5 in Wilson disease or hyperthyroidism. [6]
In statistics, an effect size is a value measuring the strength of the relationship between two variables in a population, or a sample-based estimate of that quantity. It can refer to the value of a statistic calculated from a sample of data, the value of one parameter for a hypothetical population, or to the equation that operationalizes how statistics or parameters lead to the effect size ...
Enzyme activity is commonly used for e.g. liver function tests like AST, ALT, LD and γ-GT in Sweden. [ 5 ] Percentages and time-dependent units (mol/s) are used for calculated derived parameters, e.g. for beta cell function in homeostasis model assessment or thyroid's secretory capacity .
This is termed the albumin/creatinine ratio (ACR) [10] and microalbuminuria is defined as ACR ≥3.5 mg/mmol (female) or ≥2.5 mg/mmol (male), [11] or with both substances measured by mass, as an ACR between 30 and 300 μg albumin/mg creatinine. [12] For the diagnosis of microalbuminuria, care must be taken when collecting sample for the urine ...
The waist-to-height ratio (WHtR, [a] or WSR: waist-to-stature ratio) is the waist circumference divided by body height, both measured in the same units. WHtR is a measure of the distribution of body fat. Higher values of WHtR indicate higher risk of obesity-related cardiovascular diseases, which are correlated with abdominal obesity. [1]
Cardiac index is a critical parameter in evaluating cardiac performance and the adequacy of tissue perfusion. In healthy adults, the normal range of cardiac index is generally between 2.6 to 4.2 L/min/m².