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  2. Coronavirus spike protein - Wikipedia

    en.wikipedia.org/wiki/Coronavirus_spike_protein

    The spike protein is responsible for viral entry into the host cell, a required early step in viral replication. It is essential for replication. [ 2 ] It performs this function in two steps, first binding to a receptor on the surface of the host cell through interactions with the S1 region, and then fusing the viral and cellular membranes ...

  3. Elimination reaction - Wikipedia

    en.wikipedia.org/wiki/Elimination_reaction

    An elimination reaction is a type of organic reaction in which two substituents are removed from a molecule in either a one- or two-step mechanism. [2] The one-step mechanism is known as the E2 reaction, and the two-step mechanism is known as the E1 reaction. The numbers refer not to the number of steps in the mechanism, but rather to the ...

  4. Nuclease S1 - Wikipedia

    en.wikipedia.org/wiki/Nuclease_S1

    Nuclease S1 (EC 3.1.30.1) is an endonuclease enzyme that splits single-stranded DNA (ssDNA) and RNA into oligo- or mononucleotides. This enzyme catalyses the following chemical reaction Endonucleolytic cleavage to 5'-phosphomononucleotide and 5'-phosphooligonucleotide end-products

  5. Electron transport chain - Wikipedia

    en.wikipedia.org/wiki/Electron_transport_chain

    An electron transport chain (ETC [1]) is a series of protein complexes and other molecules which transfer electrons from electron donors to electron acceptors via redox reactions (both reduction and oxidation occurring simultaneously) and couples this electron transfer with the transfer of protons (H + ions) across a membrane.

  6. Pyruvate dehydrogenase complex - Wikipedia

    en.wikipedia.org/wiki/Pyruvate_dehydrogenase_complex

    The E2 subunit from pyruvate dehydrogenase evolved from the E2 gene found in BCOADH while both enzymes contain identical E3 subunits due to the presence of only one E3 gene. Since the E1 subunits have a distinctive specificity for particular substrates, the E1 subunits of pyruvate dehydrogenase and BCOADH vary but share genetic similarities.

  7. SN1 reaction - Wikipedia

    en.wikipedia.org/wiki/SN1_reaction

    Formation of a tert-butyl carbocation by separation of a leaving group (a bromide anion) from the carbon atom: this step is slow. [5] Recombination of carbocation with nucleophile. Nucleophilic attack: the carbocation reacts with the nucleophile. If the nucleophile is a neutral molecule (i.e. a solvent) a third step is required to complete the ...

  8. Protein production - Wikipedia

    en.wikipedia.org/wiki/Protein_production

    [11] [12] Overexpression is an abnormally and excessively high level of gene expression which produces a pronounced gene-related phenotype. [ 13 ] [ 14 ] [ clarification needed ] There are many ways to introduce foreign DNA to a cell for expression, and many different host cells may be used for expression — each expression system has distinct ...

  9. Protein biosynthesis - Wikipedia

    en.wikipedia.org/wiki/Protein_biosynthesis

    Once transcription is complete, the pre-mRNA molecule undergoes post-transcriptional modifications to produce a mature mRNA molecule. [citation needed] There are 3 key steps within post-transcriptional modifications: [citation needed] Addition of a 5' cap to the 5' end of the pre-mRNA molecule