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Increased concentrations of nortriptyline may increase the risk for side effects, including anticholinergic and nervous system adverse effects, while decreased concentrations may reduce the drug's efficacy. [39] [40] [41] Individuals can be categorized into different types of CYP2D6 metabolizers depending on which genetic variations they carry ...
Its side effects are especially noticeable early in therapy. [6] In most people, early TCA side effects decrease or disappear entirely with time, but, until then, patients taking protriptyline should take care to assess which side effects occur in them and should not perform hazardous activities requiring mental acuity or coordination. [ 8 ]
The most common side effects are dry mouth, drowsiness, dizziness, constipation, and weight gain. Glaucoma , liver toxicity and abnormal heart rhythms are rare but serious side effects. Blood levels of amitriptyline vary significantly from one person to another, [ 17 ] and amitriptyline interacts with many other medications potentially ...
Side effects may also be less troublesome if treatment is initiated with low doses and then gradually increased, although this may also delay the beneficial effects. TCAs can behave like class 1A antiarrhythmics , as such, they can theoretically terminate ventricular fibrillation, decrease cardiac contractility and increase collateral blood ...
Nortriptyline (Pamelor, Aventyl) Noxiptiline (Agedal, Elronon, Nogedal) Pipofezine (Azafen/Azaphen) Protriptyline (Vivactil) Trimipramine (Surmontil) Opipramol (Insidon), tianeptine (Stablon, Coaxil) and amineptine (discontinued; formerly Survector, Maneon) are chemically TCAs but are pharmacodynamically atypical, and are therefore grouped ...
Cialis has several common side effects, many of which also happen with other drugs used to treat ED, like sildenafil (generic Viagra®), vardenafil , and avanafil (Stendra®).