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The most serious and common adverse side effects associated with anticoagulants are increased risk of bleeding, both nonmajor and major bleeding events. [37] The bleeding risk depends on the class of anticoagulant agent used, the patient's age, and pre-existing health conditions.
Side effects may include bleeding, most commonly from the nose, gastrointestinal tract (GI) or genitourinary system. [2] Compared to the risk of bleeding with warfarin use, direct factor Xa inhibitors have a higher risk of GI bleeding, but lower risk of bleeding in the brain. [2]
Warfarin is indicated for the prophylaxis and treatment of venous thrombosis and its extension, pulmonary embolism; [9] prophylaxis and treatment of thromboembolic complications associated with atrial fibrillation and/or cardiac valve replacement; [9] and reduction in the risk of death, recurrent myocardial infarction, and thromboembolic events such as stroke or systemic embolization after ...
Its anticoagulant properties make it useful to prevent blood clotting in blood specimen test tubes and kidney dialysis machines. [4] [6] Common side effects include bleeding, pain at the injection site, and low blood platelets. [3] Serious side effects include heparin-induced thrombocytopenia. [3] Greater care is needed in those with poor ...
Common side effects include bleeding. [8] Other serious side effects may include spinal hematoma and anaphylaxis. [8] It is unclear if use in pregnancy and breastfeeding is safe. [1] Compared to warfarin it has fewer interactions with other medications. [9] It works by blocking the activity of the clotting protein factor Xa. [8]
Warfarin has a low molecular weight so can pass from the maternal to fetal bloodstream through the tight filter-like junctions of the placental barrier. As the teratogenic effects of warfarin are well known, the medication is rarely prescribed to pregnant women. However, for some patients, the risks associated with discontinuing warfarin use ...
Common side effects include bleeding and nausea. [8] [9] Other side effects may include bleeding around the spine and allergic reactions. [8] Use is not recommended during pregnancy or breastfeeding. [1] [9] Use appears to be relatively safe in those with mild kidney problems. [9] Compared to warfarin it has fewer interactions with other ...
Other side effects may include bleeding around the spine and allergic reactions such as anaphylaxis. [6] In cases of severe bleeding, it can be reversed with the antidote, idarucizumab. [6] Use is not recommended during pregnancy or breastfeeding. [6] Compared to warfarin it has fewer interactions with other medications. [9]