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"Endometriosis is largely a quality of life issue that centers on symptoms related to pain," says Dr. Wasson. "Therefore, treatment should be centered on improving and optimizing quality of life ...
Diagnosis of EIN lesions is of clinical importance because of the increased risk of coexisting (39% of women with EIN will be diagnosed with carcinoma within one year) or future (the long term endometrial cancer risk is 45 times greater for a woman with EIN compared to one with only a benign endometrial histology) endometrial cancer.
Endometriosis can also impact a woman's fetus or neonate, increasing the risks for congenital malformations, preterm delivery and higher neonatal death rates. [46] Endometriosis can lead to ovarian cysts (endometriomas), adhesions, and damage to the fallopian tubes or ovaries, all of which can interfere with ovulation and fertilization.
The presence of transitional lesions (atypical endometriosis, borderline tumors) linking endometriosis to its malignant transformation is termed endometriosis-correlated ovarian cancer while the simple presence of endometriosis and ovarian cancer without the proof of transition is termed endometriosis-incidental ovarian cancer. [37]
What is endometriosis, a condition affecting more than 5 million women in the U.S.? Get answers in this Q&A with a surgical expert in the field.
There is an association with endometriosis and concurrent primary endometrial carcinoma (endometrial cancer). On gross pathological examination, the tumor is cystic and may be solid and some arise in cystic endometriosis. In 40% of cases, endometrioid tumors are found bilaterally.
In the case of endometriosis, for example, there is no cure — the condition can only be treated. “But you want to do what you can to change the modifiable risk factors you have,” Wong says.
Endometrioma is found in 17–44% patients with endometriosis. [2] More broadly, endometriosis is the presence of tissue similar to, but distinct from, endometrial tissue located outside the uterus. The presence of endometriosis can result in the formation of scar tissue, adhesions and an inflammatory reaction.
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