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Naltrexone/bupropion, sold under the brand name Contrave among others, is a fixed-dose combination medication for the management of chronic obesity in adults in combination with a reduced-calorie diet and increased physical activity. [4] [6] It contains naltrexone, an opioid antagonist, and bupropion, an aminoketone atypical antidepressant. [4]
Qsymia Phentermine is a substituted amphetamine and topiramate has an unknown mechanism of action Approved for weight management (short-term) by the FDA but not the European Medicines Agency [54] 10% [55] or 8.25 kilograms (18.2 lb) [56] Naltrexone/bupropion: Contrave Approved for weight management (chronic) in the US and EU [57] 5 percent [17 ...
Wegovy is approved for people with a body mass index (BMI) of 30 or more, or 27 or more with at least one weight-related condition, like high blood pressure, high cholesterol or type 2 diabetes.
In clinical trials, the most common adverse events which occurred at a rate ≥5% and ≥1.5 times placebo included paraesthesia (tingling in fingers/toes), dizziness, altered taste, insomnia, constipation, and dry mouth.
Only 13% of patients who started taking Contrave from Orexigen Therapeutics and 10% of those who started on Qsymia from Vivus between 2015 and 2022 were still filling their prescriptions a year ...
It's sold under the names Xenical and Alli. Phentermine-topiramate. Sold under the brand name Qsymia, it is a combination of the drugs phentermine and topiramate, which are taken orally. The ...
Nonetheless, findings from a randomized clinical trial suggest that this effect may be mediated by a reduction in blood pressure, indicating that sodium reduction may decrease headache if it significantly lowers blood pressure. [48] The treatment of chronic headaches through changes in diet is based on personal opinion, and, therefore ...
High blood pressure crisis and headaches. If your blood pressure is 180/120 mm Hg or higher and you have chest pain, back pain, or vision changes, you may be having a hypertensive emergency ...