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Unlike the gastric folds in the stomach, they are permanent, and are not obliterated when the intestine is distended.. The spaces between circular folds are smaller than the haustra of the colon, and, in contrast to haustra, circular folds reach around the whole circumference of the intestine.
Folds form under varied conditions of stress, pore pressure, and temperature gradient, as evidenced by their presence in soft sediments, the full spectrum of metamorphic rocks, and even as primary flow structures in some igneous rocks. A set of folds distributed on a regional scale constitutes a fold belt, a common feature of orogenic zones.
Circular folds are transverse folds that slow the passage of the luminal contents and serve to expand the total surface area threefold. Villi and intestinal glands serve to increase the mucosal surface area tenfold. (Intestinal villus) Microvilli covering the apical surface of the enterocytes increase the absorptive surface twentyfold.
These folds together with villi serve to increase the surface area of the jejunum enabling an increased absorption of digested sugars, amino acids and fatty acids into the bloodstream. The circular folds also slow the passage of food giving more time for nutrients to be absorbed. The last part of the small intestine is the ileum.
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These folds are about 12 mm. in width and are composed of the circular muscle coat of the rectum. They are usually three in number; sometimes a fourth is found, and occasionally only two are present. One is situated near the commencement of the rectum, on the right side.
The jejunum is the second part of the small intestine in humans and most higher vertebrates, including mammals, reptiles, and birds.Its lining is specialized for the absorption by enterocytes of small nutrient molecules which have been previously digested by enzymes in the duodenum.
Anal columns (Columns of Morgagni or less commonly Morgagni's columns) are a number of vertical folds, produced by an infolding of the mucous membrane and some of the muscular tissue in the upper half of the lumen of the anal canal. They are named after Giovanni Battista Morgagni, who has several other eponyms named after him.