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The pentose phosphate pathway. The pentose phosphate pathway (also called the phosphogluconate pathway and the hexose monophosphate shunt or HMP shunt) is a metabolic pathway parallel to glycolysis. [1] It generates NADPH and pentoses (five-carbon sugars) as well as ribose 5-phosphate, a precursor for the synthesis of nucleotides. [1]
This reaction is a component of the hexose mono-phosphate shunt and pentose phosphate pathways (PPP). [2] [3] Prokaryotic and eukaryotic 6PGD are proteins of about 470 amino acids whose sequences are highly conserved. [4]
Glucose-6-phosphate dehydrogenase (G6PD) is an enzyme in the pentose phosphate pathway (see image, also known as the HMP shunt pathway). G6PD converts glucose-6-phosphate into 6-phosphoglucono-δ-lactone and is the rate-limiting enzyme of this metabolic pathway that supplies reducing energy to cells by maintaining the level of the reduced form ...
The Uptake of Hexose Phosphates (Uhp) is a protein system found in bacteria. It is a type of two-component sensory transduction pathway which helps bacteria react to their environment. [ 1 ]
100198 Ensembl ENSG00000049239 ENSMUSG00000028980 UniProt O95479 Q8CFX1 RefSeq (mRNA) NM_001282587 NM_004285 NM_001291004 NM_173371 RefSeq (protein) NP_001269516 NP_004276 NP_001277933 NP_775547 Location (UCSC) Chr 1: 9.23 – 9.27 Mb Chr 4: 150.06 – 150.09 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse GDH/6PGL endoplasmic bifunctional protein is a protein that in humans is ...
Hexose monophosphate shunt, an alternative name for the pentose phosphate pathway; Highly migratory species, a classification of fish; Hypermobility spectrum disorder, formerly hypermobility syndrome or HMS; HMS, a brand name of medrysone
Ribose 5-phosphate (R5P) is both a product and an intermediate of the pentose phosphate pathway. The last step of the oxidative reactions in the pentose phosphate pathway is the production of ribulose 5-phosphate. Depending on the body's state, ribulose 5-phosphate can reversibly isomerize to ribose 5-phosphate.
The glyoxylate shunt pathway is an alternative to the tricarboxylic acid (TCA) cycle, for it redirects the pathway of TCA to prevent full oxidation of carbon compounds, and to preserve high energy carbon sources as future energy sources. This pathway occurs only in plants and bacteria and transpires in the absence of glucose molecules. [13]