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Miscarriage is the most common complication of early pregnancy. [19] Among women who know they are pregnant, the miscarriage rate is roughly 10% to 20%, while rates among all fertilisation is around 30% to 50%. [1] [7] In those under the age of 35, the risk is about 10% while in those over the age of 40, the risk is about 45%. [1]
Recurrent miscarriage in itself is associated with later development of coronary artery disease with an odds ratio of approximately 2, [50] increased risk of ovarian cancer, [51] increased risk of cardiovascular complications, [52] and an increased risk of all-cause mortality of 44%, 86%, and 150% for women with a history of 1, 2, or 3 ...
Autoimmune diseases can result in systemic or localized symptoms, depending on the given disease. [8] Typical systemic symptoms include fevers, fatigue, muscle aches, joint pain, and rashes; these can be seen in diseases such as lupus or rheumatoid arthritis. Other autoimmune diseases have localized effects on specific organ or tissue types.
The optimality hypothesis states too much variability in the MHC can result in a failure of T-cells to distinguish themselves non-selves, and thereby increase the risk of autoimmune disease. This would confer greater fitness to individuals without a large degree MHC diversity. [6] [13] Autoimmune diseases are associated with MHC loci. In humans ...
Autoimmune disease Primary organ/body part affected Autoantibodies Acceptance as an autoimmune disease Prevalence rate (US) Cit. Autoimmune enteropathy: Small intestine: Anti-enterocyte antibodies Probable Rare [24] Autoimmune hepatitis: Liver: ANA, ASMA, anti-LKM1 Confirmed 1 in 10,000 to 1 in 50,000 [25] Celiac disease: Small intestine
Waiting periods and paperwork. Bell was crushed. She knew that at 18 weeks gestation, the fetus could not live outside the womb. Her doctor called in a complex family planning specialist to help.
An autoimmune disease is a condition arising from an abnormal immune response to a normal body part. [5] There are at least 80 types of autoimmune diseases. [5] Nearly any body part can be involved. Common symptoms include low-grade fever and feeling tired. [5] Often symptoms come and go. [5]
Pre-existing disease in pregnancy, or an acquired disease: A disease and condition not necessarily directly caused by the pregnancy. Diabetes mellitus in pregnancy; Lupus in pregnancy; Thyroid disease in pregnancy; Risks arising from previous pregnancies: Complications experienced during a previous pregnancy are more likely to recur. [64] [65]