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Staging breast cancer is the initial step to help physicians determine the most appropriate course of treatment. As of 2016, guidelines incorporated biologic factors, such as tumor grade, cellular proliferation rate, estrogen and progesterone receptor expression, human epidermal growth factor 2 (HER2) expression, and gene expression profiling into the staging system.
After completing her medical training, Lin focused on the diagnosis, treatment and outcomes of people with breast cancer. [4] In particular, she worked on HER2 positive breast cancer and breast cancer patients with brain metastasis. [5] [6] [7] Lin has developed novel pharmaceuticals for patients whose breast cancer has spread to the brain.
If a patient with ER+ breast cancer develops endocrine resistance, the endocrine therapy used to treat the cancer will no longer be effective. Approximately 30-50% of ER+ breast cancer patients will relapse as a result of endocrine resistance, proving it to be a predominant challenge in the treatment of ER+ breast cancer patients. [19]
Breast Cancer Research and Treatment is a scientific journal focused on the treatment of and investigations in breast cancer. It is targeted towards a wide audience of clinical researchers , epidemiologists , immunologists , or cell biologists interested in breast cancer.
These new criteria have been widely adopted and embraced by the regulatory authorities. [1] The mean response rate for new cancer drugs approved by the U.S. Food and Drug Administration, expressed as relative risk, ranges between 1.38x [3] and 2.37x. [4]
Treatment with the cancer drug restored function in the hippocampus in an Alzheimer’s mouse model. It has long been understood that glucose metabolism in the brain is disrupted by aging and ...
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