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Log reduction is a measure of how thoroughly a decontamination process reduces the concentration of a contaminant.It is defined as the common logarithm of the ratio of the levels of contamination before and after the process, so an increment of 1 corresponds to a reduction in concentration by a factor of 10.
In microbiology, in the context of a sterilization procedure, the D-value or decimal reduction time (or decimal reduction dose) is the time (or dose of an antimicrobial drug) required, at a given condition (e.g. temperature) or set of conditions, to achieve a one-log reduction, that is, to kill 90% of relevant microorganisms. [1]
It is the number of degrees the temperature has to be increased to achieve a tenfold (i.e. 1 log 10) reduction in the D-value. The D-value of an organism is the time required in a given medium, at a given temperature, for a ten-fold reduction in the number of organisms.
What is often called a "log reduction" (technically a reduction by one order of magnitude) represents a 90% reduction in microbial population. Thus a process that achieves a "6-log reduction" (10 −6 ) will theoretically reduce an initial population of one million organisms to very close to zero.
(A log 10 reduction between 6 and 7 means that 1 bacterium out of 1 million (10 6) to 10 million (10 7) bacteria survive the treatment.) The Codex Alimentarius Code of Hygienic Practice for Milk notes that milk pasteurization is designed to achieve at least a 5 log 10 reduction of Coxiella burnetii. [48]
During the year you reach full retirement age, the threshold increases while the reduction is only $1 for every $3 earned over that amount. For 2025, the earnings test threshold is $23,400 (or ...
The target of reduction in canning is the 12-D reduction of C. botulinum, which means that processing time will reduce the amount of this bacteria by a factor of 10 12. The D R for C. botulinum is 0.21 minute (12.6 seconds). A 12-D reduction will take 2.52 minutes (151 seconds).
Mice lacking BCL6 showed a 40% reduction in muscle mass compared to healthy mice, and their remaining muscle was structurally and functionally impaired. However, increasing BCL6 expression in the ...