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TetR is one of many proteins in the TetR protein family, which is so named because TetR is the most well characterized member. [2] TetR is used in artificially engineered gene regulatory networks because of its capacity for fine regulation of promoters.
In nature, the P tet promoter expresses TetR (the repressor) and TetA, the protein that pumps tetracycline antibiotic out of the cell. [ 2 ] The difference between Tet-On and Tet-Off is not whether the transactivator turns a gene on or off, as the name might suggest; rather, both proteins activate expression.
Transthyretin (TTR or TBPA) is a transport protein in the plasma and cerebrospinal fluid that transports the thyroid hormone thyroxine (T 4) and retinol to the liver. This is how transthyretin gained its name: transports thyroxine and retinol.
It’s estimated that nearly 5% of Americans above the age of 12 live with hypothyroidism, a condition that occurs when the body experiences a deficit of thyroid hormone.. The thyroid gland ...
Two of the five genes encoded by the central portion of Tn10, tetA and tetR, confer resistance to the antibiotic tetracycline. This activity of tetR forms the basis of the TetOFF assembly, a widely-used construct in synthetic gene studies. The TetA protein is an efflux pump. It has served as a model system for such proteins and has accumulated ...
After all, protein is a great way to start your day because it gives your breakfast staying power. And the Today Show’ s Al Roker might have the perfect protein-packed solution that can be taken ...
Public health experts are warning of a ‘quad-demic’ this winter. Here’s where flu, COVID, RSV, and norovirus are spreading
The TET enzymes are a family of ten-eleven translocation (TET) methylcytosine dioxygenases. They are instrumental in DNA demethylation.5-Methylcytosine (see first Figure) is a methylated form of the DNA base cytosine (C) that often regulates gene transcription and has several other functions in the genome.