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2. Pharmacokinetics - Wikipedia

   en.wikipedia.org/wiki/Pharmacokinetics

   Pharmacokinetics is based on mathematical modeling that places great emphasis on the relationship between drug plasma concentration and the time elapsed since the drug's administration. Pharmacokinetics is the study of how an organism affects the drug, whereas pharmacodynamics (PD) is the study of

3. Physiologically based pharmacokinetic modelling - Wikipedia

   en.wikipedia.org/wiki/Physiologically_based...

   The first pharmacokinetic model described in the scientific literature [2] was in fact a PBPK model. It led, however, to computations intractable at that time. The focus shifted then to simpler models, [3] for which analytical solutions could be obtained (such solutions were sums of exponential terms, which led to further simplifications.)

4. National Institute of Pharmaceutical Education and Research ...

   en.wikipedia.org/wiki/National_Institute_of...

   The National Institute of Pharmaceutical Education and Research, Hyderabad (NIPER Hyderabad) is an Indian public pharmaceutical research university. It is one of the seven schools under India's Ministry of Chemicals and Fertilizers.

5. Pharmacodynamics - Wikipedia

   en.wikipedia.org/wiki/Pharmacodynamics

   Toxicodynamics (TD) and pharmacodynamics (PD) link a therapeutic agent or toxicant, or toxin (xenobiotic)'s dosage to the features, amount, and time course of its biological action. [11] The mechanism of action is a crucial factor in determining effect and toxicity of the drug, taking in consideration the pharmacokinetic (PK) factors. [12]

6. PK/PD model - Wikipedia

   en.wikipedia.org/wiki/PK/PD_model

   It integrates a pharmacokinetic and a pharmacodynamic model component into one set of mathematical expressions that allows the description of the time course of effect intensity in response to administration of a drug dose. PK/PD modeling is related to the field of pharmacometrics.

7. Pharmacokinetics simulation - Wikipedia

   en.wikipedia.org/wiki/Pharmacokinetics_simulation

   Pharmacokinetics simulation gives an insight to drug efficacy and safety before exposure of individuals to the new drug that might help to improve the design of a clinical trial. Pharmacokinetics simulations help in addition in therapy planning, to stay within the therapeutic range under various physiological and pathophysiological conditions ...