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Post-cardiac arrest syndrome (PCAS) is an inflammatory state of pathophysiology that can occur after a patient is resuscitated from a cardiac arrest. [1] While in a state of cardiac arrest, the body experiences a unique state of global ischemia .
The underlying causes of sudden cardiac arrest can result from cardiac and non-cardiac etiologies. The most common underlying causes are different, depending on the patient's age. Common cardiac causes include coronary artery disease , non-atherosclerotic coronary artery abnormalities, structural heart damage, and inherited arrhythmias.
Patients with sustained ROSC generally present with post-cardiac arrest syndrome (PCAS). Longer time-to-ROSC is associated with a worse presentation of PCAS. [9] Lazarus phenomenon is the rare spontaneous return of circulation after cardiopulmonary resuscitation attempts have stopped in someone with cardiac arrest. This phenomenon most ...
Pulseless electrical activity (PEA) is a form of cardiac arrest in which the electrocardiogram shows a heart rhythm that should produce a pulse, but does not.Pulseless electrical activity is found initially in about 20% of out-of-hospital cardiac arrests [1] and about 50% of in-hospital cardiac arrests.
Agonal respirations are commonly seen in cases of cardiogenic shock (decreased organ perfusion due to heart failure) or cardiac arrest (failure of heartbeat), where agonal respirations may persist for several minutes after cessation of heartbeat.
Patients having a significant collateral circulation can live to adulthood in rare cases, but often insufficient circulation will cause them to develop chronic ischemia, having a risk for sudden cardiac arrest, heart failure or malignant arrhythmia. [3] [4] The mechanism of patient survival to adulthood is not fully understood. [4]
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Acidosis (hydrogen cation excess) is an abnormal pH in the body as a result of lactic acidosis which occurs in prolonged hypoxia and in severe infection, diabetic ketoacidosis, kidney failure causing uremia, or ingestion of toxic agents or overdose of pharmacological agents, such as aspirin and other salicylates, ethanol, ethylene glycol and other alcohols, tricyclic antidepressants, isoniazid ...